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Myobloc for Hyperhidrosis : Techniques
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Palms
To treat hyperhidrosis of the palms, the dose used is 5,760 Myobloc units per palm for a total dose of 11,520 units. The Myobloc 5,000 unit vial (5000 units in 1cc) is diluted with 1.0cc of saline in the vial. (Either saline containing benzoic acid or preservative-free saline can be used). Note that the vials are overfilled, therefore the dilution would differ if you dilute in the syringe. See dilution tables for more information.
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This dilution technique, when performed in the vial, yields 288 units per 0.1cc of solution or 144 units per 0.05cc of solution. This dilution allows one to inject 40 injections of 0.05 cc per palm, resulting in a total dose of 5,760 per palm. The injections are scattered approximately every 2 square centimeters. Approximately 25 will be scattered on the palm of the hand and 15 will be scattered on the fingertips, tip and web of hand. Using a 1cc tuberculin syringe with a 30-gauge needle, subcutaneously inject 0.05cc with an approximate depth of 3mm with care to avoid intramuscular injections.
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