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Myobloc for Hyperhidrosis : Techniques
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Soles
To treat hyperhidrosis of the soles, the dose used is 5,760 Myobloc units per palm for a total dose of 11,520 units. The Myobloc 5,000 unit vial (5000 units in 1cc) is diluted with 1.0cc of saline in the vial. (Either saline containing benzoic acid or preservative-free saline can be used). Note that the vials are overfilled, therefore the dilution would differ if you dilute in the syringe. See dilution tables for more information.
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Injection Sites
This dilution technique, when performed in the vial, yields 288 units per 0.1cc of solution or 144 units per 0.05cc of solution. This dilution allows one to inject 40 injections of 0.05 cc per sole, resulting in a total dose of 5,760 per palm. Using a 1cc tuberculin syringe with a 30-gauge needle, subcutaneously inject 0.05cc with an approximate depth of 3mm with care to avoid intramuscular injections. The injections are scattered approximately every 2 square centimeters. Approximately 30 will be scattered on the sole and the sides of the sole and 10 will be placed in the webs between the toes and on the tips of the toes.
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